Pretend its a real PS2. You put the disc in the drive and it goes through the bios first, then runs the game. If the BIOS isn't detecting the game, make sure your CDVD plugin is NOT set to CDVDnull. If you are using a ISO, use Linuzappz's ISO plugin. If you're using a real disc, make sure your drive can read DVD's (if the game is on DVD) and use the P.E.O.Ps CDVD plugin. I suggest using an ISO.
A CVS version is a version still in development. I'm not sure whether forum rules allow me to post a link so send me a PM and i'll give you a link.